anti-HDAC6 antibody
ARG20183
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse
TargetHdac6
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-HDAC6 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID15185
- Target nameHdac6
- Target descriptionhistone deacetylase 6
- Target synonymsHd6; Hdac5; histone deacetylase 5; histone deacetylase 6; histone deacetylase mHDA2; mHDA; mHDA2; scurfy candidate 6; Sfc; Sfc6; tubulin-lysine deacetylase HDAC6
- HostRabbit
- IsotypeIgG
- Scientific DescriptionHuman HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
- ReactivityMouse
- Storage Instruction-20°C
- UNSPSC12352203