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anti-HDAC6 antibody

ARG20183
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse
TargetHdac6
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-HDAC6 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID15185
  • Target name
    Hdac6
  • Target description
    histone deacetylase 6
  • Target synonyms
    Hd6; Hdac5; histone deacetylase 5; histone deacetylase 6; histone deacetylase mHDA2; mHDA; mHDA2; scurfy candidate 6; Sfc; Sfc6; tubulin-lysine deacetylase HDAC6
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203