anti-HDAC6 antibody

Arigo Biolaboratories

anti-HDAC6 antibody

23

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

Hdac6

histone deacetylase 6

Hd6; Hdac5; histone deacetylase 5; histone deacetylase 6; histone deacetylase mHDA2; mHDA; mHDA2; scurfy candidate 6; Sfc; Sfc6; tubulin-lysine deacetylase HDAC6

Rabbit

IgG

Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.

Mouse

-20°C

12352203