anti-HDAC7 antibody

Arigo Biolaboratories

anti-HDAC7 antibody

23

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

Hdac7

histone deacetylase 7

5830434K02Rik; HD7; HD7a; Hdac; Hdac7a; histone deacetylase 7; histone deacetylase 7A; mFLJ00062

Rabbit

IgG

Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

-20°C

12352203