Anti-HDAC8 (Phospho-Ser39)

Applied Biological Materials

Anti-HDAC8 (Phospho-Ser39)

9

HDAC8 (phospho-Ser39) antibody detects endogenous levels of HDAC8 only when phosphorylated at serine 39.

ImmunoHistoChemistry

Research Use Only

Polyclonal

1 ug/ul

Rabbit

Phosphorylated

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203