Anti-Hepcidin-25 [AN-LP1]

Absolute Antibody

Anti-Hepcidin-25 [AN-LP1]

7

The original mouse IgG1 antibody binds human hepcidin-25 with a binding affinity of Kd= 99 pM. The binding characterization of this antibody to synthetic human hepcidin-25 was done using ELISA. This antibody can be used for the identification of synthetic human hepcidin or human hepcidin from the sera of patients with an inflammatory disease using dot blot and western blot. This antibody was also used for the immunohistochemical analysis of paraffine-embedded human liver biopsies. The biological activity of this antibody was tested by incubating this antibody with macrophages from J774 murine cell line, and it was reported that this antibody induces ferroprotein degradation (US8487081).

Functional Assay, Western Blot, ELISA, ImmunoHistoChemistry

ELISA; WB; IHC; functional assay

Research Use Only

Hepcidin

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203