Anti-HER2/ErbB2 Rabbit mAb
PTM-5068
ApplicationsImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
Overview
- SupplierPTM BIO
- Product NameAnti-HER2/ErbB2 Rabbit mAb
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry Paraffin
- Applications SupplierIHC-P
- Category SupplierAntibody
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJRMR-121
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Protein IDP04626
- Protein NameReceptor tyrosine-protein kinase erbB-2
- Scientific DescriptionThe ErbB family of receptor tyrosine kinases, consisting of the epidermal growth factor (EGF)1 receptor ErbB1, ErbB2/ Neu, ErbB3, and ErbB4, binds a large group of ligands, the EGF-related peptides. Upon ligand-induced dimerization, the receptors autoPhosphorylatedrylate on specific tyrosine residues in their cytoplasmic tails. These residues provide docking sites for hosphotyrosine binding, cytoplasmic signaling molecules hat activate numerous intracellular signaling pathways.
- Shelf life instructionStable for 12 months from date of receipt/reconstitution.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteProtein A purified
- Storage InstructionStore at -20°C. Avoid freeze/thaw cycles.
- UNSPSC12352203