Anti-hINSR [IR 18-146]

Absolute Antibody

Anti-hINSR [IR 18-146]

7

This confirmation-dependent antibody is specific for human INSR, reacting with an epitope within the CR domain of the alpha subunit (amino acids 191-290). It does not cross-react with rat, mouse or rabbit INSR, and displays low cross-reactivity with bovin

This antibody has been used in immunoprecipitation assays, with both radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has been shown to enhance insulin binding to IM-9 cells (Soos et al, 1986).

ImmunoPrecipitation, Other Application

IP; stimulatory

Research Use Only

Monoclonal

IR 18-146

INSR

insulin receptor

CD220; HHF5; insulin receptor; IR

Rabbit

IgG

Insulin receptor

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antibody was raised by immunising BALB/c mice with purified human placental insulin receptor.

-20°C,2°C to 8°C

12352203