Anti-hINSR [IR 83-16]

Absolute Antibody

Anti-hINSR [IR 83-16]

7

This antibody reacts with human INSR, recognising an epitope on the alpha subunit (amino acids 191-290). It does not cross-react with rat insulin receptors, and does cross-react with rabbit, bovine, porcine and ovine receptors.

This antibody has been used in immunoprecipitation assays, with radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has been shown to enhance insulin binding to IM-9 cells (Soos et al, 1986).

ImmunoPrecipitation, Other Application

IP; stimulatory

Research Use Only

Monoclonal

IR 83-16

INSR

insulin receptor

CD220; HHF5; insulin receptor; IR

Human

IgG1

Insulin receptor

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Bovine, Human, Rabbit

Human, rabbit, bovine

This antibody was raised by immunising BALB/c mice with IM-9 lymphocytes, and boosting with purified human placental insulin receptor prior to fusion.

-20°C,2°C to 8°C

12352203