Anti-HIV-1 surface protein gp120 [694-D], Human IgG1, lambda

Absolute Antibody

Anti-HIV-1 surface protein gp120 [694-D], Human IgG1, lambda

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This antibody is specific for the GRAF sequence of the gp120 V3 loop of HIV-1.

The original version of this antibody (human IgG1) was characterized for its specificity and reactivity using ELISA and IB assays. In the ELISA, it reacted with the V3 of HIV strains MN, SF-2, HXB2, RF, WM52, NY5, SC, and CDC4 with an affinity (Kd) of 1.8 microM and 12.0 microM for SF-2 and HXB2, respectively. In an IB, this antibody reacted with gp120HTLV-IIIB. In in vitro neutralization assays, this antibody exhibited neutralizing activity against multiple HIV-1 strains, exhibiting broad reactivity (US5914109A).

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

694-D

Human

IgG1

Envelope glycoprotein gp160

Virus

-20°C,2°C to 8°C

12352203