anti-HLA DR1 (empty) antibody [MEM-267] (PE)

Arigo Biolaboratories

anti-HLA DR1 (empty) antibody [MEM-267] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

MEM-267

0.1 mg/ml

RPE

HLA-DRB1

major histocompatibility complex, class II, DR beta 1

DRB1; HLA class II histocompatibility antigen, DR-1 beta chain; HLA-DR1B; HLA-DRB; human leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex, class II, DR beta 1 precursor; MHC class II HLA-DR beta 1 chain; SS1

Mouse

IgG2b

HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.

2°C to 8°C

12352203