Anti-HLA/EBNA1 [anti-HLA-A0201/EBNA1 antibody]

Absolute Antibody

Anti-HLA/EBNA1 [anti-HLA-A0201/EBNA1 antibody]

9

The antibody targets Epstein-Barr virus (EBV) associated tumor cells by binding to HLA/EBNA1 peptide complexes. The antibody recognizes EBNA1 epitope presented on HLA-A0201, HLA-A203, HLA-A0206 and HLA-A0207. Epstein-Barr Virus (EBV) is a ubiquitous human

The antibody is specific for EBV-EBNA-1, as detected by FC. The binding affinity of the original format of the antibody to HLA-A0201/EBNA-1 was measured by surface plasmon resonance (Kd= 6.02nM). This antibody was used for detection of HLA-A0201/EBNA1 complexes expressed on CCRF-SB and RPMI6666 tumour cells by flow cytometry. The antibody was used for immunological staining of EBV infected-HLA-A0201 positive nasopharyngeal carcinoma (NPC) biopsy. This biopsy was observed to stain positive for HLA-A0201/EBNA1 complexes (WO2015199617A1).

Flow Cytometry, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

anti-HLA-A0201/EBNA1 antibody

EBNA-1

protein-coding

HHV4_EBNA-1.1

Human

IgG1

Epstein-Barr nuclear antigen 1

Virus

-20°C,2°C to 8°C

12352203