Anti-Hu CD184 PE-Cy(tm)7
T7-146
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Primate
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD184 PE-Cy(tm)7
- Delivery Days Customer7
- Antibody SpecificityThe mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
- Application Supplier NoteFlow cytometry: The reagent is designed for analysis of human blood cells using 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone ID12G5
- ConjugateDouble Conjugated
- IsotypeIgG2a
- Scientific DescriptionCD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.
- ReactivityHuman, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203