Anti-Hu CD273 Purified

EXBIO

Anti-Hu CD273 Purified

7

The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung

Flow cytometry: Recommended dilution: 1-4 microg/ml

Flow Cytometry, ImmunoHistoChemistry

Research Use Only

24F.10C12

1 mg/ml

IgG2a

CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.

Human

2°C to 8°C

12352203