Anti-Hu CD319 Alexa Fluor(r) 647

EXBIO

Anti-Hu CD319 Alexa Fluor(r) 647

7

The mouse monoclonal antibody 162 recognizes an extracellular epitope of human CD319, a transmembrane glycoprotein expressed by cytotoxic T cells, activated B cells, NK cells, and mature dendritic cells.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

162

AlexaFluor 647

IgG2b

CD319 is a homophilic type I transmembrane protein with two intracellular immunoreceptor tyrosine-based switch motives (ITSMs). It is expressed by cytotoxic T cells, activated B cells and plasma cells, NK cells, and mature dendritic cells. CD319 triggers NK cell-mediated cytotoxicity. Ligation of CD319 can induce proliferation, cell adhesion, cytokine secretion, and cytotoxicity of T cells and NK cells.

Human

2°C to 8°C

12352203