Anti-Hu CD44 APC-Cy(tm)7
T4-221
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD44 APC-Cy(tm)7
- Delivery Days Customer7
- Antibody SpecificityThe antibody MEM-85 reacts with an extracellular antigen of both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leuk
- Application Supplier NoteFlow cytometry: The reagent is designed for analysis of human blood cells using 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone IDMEM-85
- ConjugateDouble Conjugated
- IsotypeIgG2b
- Scientific DescriptionCD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203