Anti-Hu CD57 PE-Cy(tm)7

EXBIO

Anti-Hu CD57 PE-Cy(tm)7

7

The mouse monoclonal antibody TB01 recognizes CD57, a carbohydrate extracellular antigen present mainly on NK cells, NK T cells, and in neural tissue.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Flow Cytometry

Research Use Only

TB01

Double Conjugated

IgM

CD57, also known as HNK1 or Leu7, is a sulphated trisaccharide (3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc) attached to several glycoproteins, including CD56, myelin glycoprotein PO, and neural cell adhesion molecule L1, as well as on glycolipids and chondroitin sulphate proteoglycans in the nervous system. It serves as a NK cell marker and it is expressed on well differentiated prostate cancers and uveal and cutaneous melanoma. CD57+ T cells are implicated as suppressors of T-cell responses.

Human

2°C to 8°C

12352203