Anti-Human Chorionic Gonadotropin [AB4]

Absolute Antibody

Anti-Human Chorionic Gonadotropin [AB4]

7

The antibody binds specifically to hCG, a hormone produced by a part of the placenta, the syncytiotrophoblast, following implantation. The hormone has an important role during pregnancy, as it interacts with the LHCG receptor in the ovaries to prevent the degeneration of the corpus luteum, and thereby allows the secretion of progesterone during the first trimester. hCG is a heterodimeric glycoprotein, composed of an alpha and a beta domain, of which the alpha is identical to that of LH and FSH, while the beta is unique to hCG. The monoclonal antibody AB4 is specific for the beta-subunit, and can be used in the detection of the hormone in pregnancy tests or in the diagnosis of uterine cancer.

ELISA, ImmunoHistoChemistry, RadioImmunoAssay

ELISA; RIA; IHC

Research Use Only

Monoclonal

AB4

CGB3

chorionic gonadotropin subunit beta 3

CGB; CGB5; CGB7; CGB8; CG-beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin, beta polypeptide; hCGB; LHB; luteinizing hormone beta subunit

Human

IgG1

Choriogonadotropin subunit beta 7

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

Human chorionic gonadotropin.

-20°C,2°C to 8°C

12352203