Anti Human CRK Polyclonal

Applied Biological Materials

Anti Human CRK Polyclonal

9

Western Blot, ELISA

Research Use Only

Polyclonal

1 ug/ul

Rabbit

IgG

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C,2°C to 8°C

12352203