Anti-Human Muscle Acetylcholine Receptor [mAb 192]

Absolute Antibody

Anti-Human Muscle Acetylcholine Receptor [mAb 192]

7

The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.

This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding.

Western Blot, ELISA, Neutralisation/Blocking

ELISA; WB; Blocking

Research Use Only

Monoclonal

mAb 192

CHRNA1

cholinergic receptor nicotinic alpha 1 subunit

acetylcholine receptor subunit alpha; acetylcholine receptor, nicotinic, alpha 1 (muscle); ACHRA; ACHRD; cholinergic receptor, nicotinic alpha 1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle); CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; muscle nicotinic acetylcholine receptor; nicotinic acetylcholine receptor alpha subunit; nicotinic cholinergic receptor alpha 1; SCCMS

Mouse

IgG2a

Acetylcholine receptor subunit alpha

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rat

Human, Mouse, Rat

Human muscle AChR.

-20°C,2°C to 8°C

12352203