Anti-IDH1 R132H [10G5-1]

Absolute Antibody

Anti-IDH1 R132H [10G5-1]

9

This antibody binds human isocitrate dehydrogenase 1 (IDH1) having R132H mutation. IDH1 is an enzyme that catalyzes the NADP+-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by

The binding reactivity of this antibody to R132H mutant of human IDH1 was determined using ELISA. The original mouse IgG antibody binds IDH1 R132H mutant with an affinity of Kd= 5.76 X10 ^(-10) M. This antibody was used in the immunohistochemical analysis for detection of IDH1 R132H protein in cancerous tissues (CN108727500).

ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

10G5-1

IDH1

isocitrate dehydrogenase (NADP(+)) 1

epididymis luminal protein 216; epididymis secretory protein Li 26; epididymis secretory sperm binding protein; HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; isocitrate dehydrogenase (NADP(+)) 1, cytosolic; isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase 1 (NADP+), soluble; NADP(+)-specific ICDH; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal; oxalosuccinate decarboxylase; PICD

Human

IgG1

Isocitrate dehydrogenase [NADP] cytoplasmic

Human

-20°C,2°C to 8°C

12352203