Anti-IgG-Fc Domain [IgG-Fc-16], Human IgG1-Fc Fusion,

Absolute Antibody

Anti-IgG-Fc Domain [IgG-Fc-16], Human IgG1-Fc Fusion,

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This antibody is specific for the mammalian IgG-Fc domain. It was tested for and found to bind the human IgG-Fc domain (all subclasses). In a cross-reactivity test, it also bound bovine, mouse, rat, rabbit, dog, cat, swine, sheep, Chimpanzee, Rhesus macaq

The reactivity of the original version of this antibody (camelid (llama) VHH) was tested using ELISA. Its binding affinity (KD) was measured using SPR and was found to be 13.1, 6.81, 16.2, 21.3, 1.70, 2.79, and 8.41 nM for human IgG, human IgG1, human IgG2, human IgG3, human IgG4, bovine IgG, and mouse IgG, respectively. Its binding to human, mouse, and bovine IgG was further verified via chromatography testing; the dynamic binding capacity of the antibody when immobilized onto NHS sepharose was 11.5 mg human IgG/ml matrix (US9040666B2).

ELISA, Other Application

Research Use Only

Monoclonal

IgG-Fc-16

Human

IgG1

This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Bovine, Canine, Donkey, Equine, Feline, Guinea Pig, Goat, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat, Sheep

-20°C,2°C to 8°C

12352203