Anti-IgNAR [GA8]

Absolute Antibody

Anti-IgNAR [GA8]

9

This antibody is specific for IgNAR, an Ig heavy chain isotype specific to elasmobranchs, and reacts with an epitope in the constant domain. This anti-nurse shark IgNAR antibody has been shown to cross-react with spiny dogfish IgNAR.

This antibody immunoprecipitates IgNAR from both nurse shark and spiny dogfish plasma (Smith et al, 2012), and from serum and yolk extracts from mature unfertilized nurse shark eggs (Haines et al, 2005). This antibody has been used in immunohistochemical analysis of IgNAR expression in frozen sections of nurse shark spleen, to identify its cellular organisation (Rumfelt et al, 2002). This antibody has been used in ELISA analysis to measure plasma titres of IgNAR following spiny dogfish immunisation with human serum albumin (Muller et al, 2012) and nurse shark immunisation with human and murine induced costimulatory ligand (Kovaleva et al, 2017) and with recombinant human TNF-alpha (Ubah et al, 2017).

ImmunoPrecipitation, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

GA8

Mouse

IgG2a

Fish

-20°C,2°C to 8°C

12352203