anti-IKK-gamma, pAb

AdipoGen Life Sciences

anti-IKK-gamma, pAb

10

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Polyclonal

IKBKG

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

14.7K (adenovirus E3 protein) interacting protein 3; AMCBX1; EDAID1; FIP3; FIP-3; Fip3p; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; IP; IP1; IP2; IPD2; NEMO; NF-kappa-B essential modifier; NF-kappa-B essential modulator; ZC2HC9

Rabbit

IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response. - Polyclonal Antibody. Recognizes human and mouse IKK-gamma. Source: Rabbit. Applications: ELISA, IP, WB. Liquid. In TRIS, pH 7.4, containing 50% glycerol. IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response.

Human, Mouse

2°C to 8°C,-20°C

12352203