anti-IKZF1 / Ikaros antibody (C-term)
ARG54055
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetIKZF1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-IKZF1 / Ikaros antibody (C-term)
- Delivery Days Customer23
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10320
- Target nameIKZF1
- Target descriptionIKAROS family zinc finger 1
- Target synonymsCLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; Hs.54452; IK1; IKAROS; ikaros family zinc finger protein 1; LYF1; LyF-1; lymphoid transcription factor LyF-1; PPP1R92; PRO0758; protein phosphatase 1, regulatory subunit 92; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionTranscription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity)
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203