Anti-IL-12/IL-23p40 [CNTO 1275 (Ustekinumab)], Rabbit IgG, kappa

Absolute Antibody

Anti-IL-12/IL-23p40 [CNTO 1275 (Ustekinumab)], Rabbit IgG, kappa

9

This antibody is specific for the p40 subunit of human IL-12/23.

This antibody inhibits the interactions of IL-12 and IL-23 with the cell surface IL-12Rbeta1 receptor and has been evaluated in phase I, II, and III trials as a treatment for immune-mediated diseases such as psoriasis, psoriatic arthritis, Crohns disease, multiple sclerosis, and ulcerative colitis (Elliott et al., 2009; PMID: 20074279) (Sands et al., 2019; PMID: 31553833).

Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

CNTO 1275 (Ustekinumab)

Rabbit

IgG

Human

-20°C,2°C to 8°C

12352203