Anti-IL-13 [DOM10-53-616]

Absolute Antibody

Anti-IL-13 [DOM10-53-616]

9

This antibody binds human interleukin-13. It is also reported to cross react with cynomolgus monkey and rhesus monkey IL13. Interleukin-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosi

The binding characterization of this antibody to human, cynomolgus monkey and rhesus monkey IL-13 was done using ELISA. The binding affinity of the original single chain VHH antibody was assessed using BIAcore analysis. It was reported that the original VHH antibody bound human and cynomolgus monkey IL13 with a binding affinity of 130 pM and 3.2 pM respectively. This antibody shows neutralizing potency for human, cynomolgus monkey and rhesus IL-13 (US20110236380).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

DOM10-53-616

IL13

interleukin 13

IL-13; interleukin-13; P600

Mouse

IgG1

Interleukin-13

This chimeric mouse antibody was made using the variable domain sequences of the original VHH format for improved compatibility with existing reagents assays and techniques.

Human, Monkey, Primate

-20°C,2°C to 8°C

12352203