Anti-IL-1B [1]

Absolute Antibody

Anti-IL-1B [1]

7

The antibody is specific for chicken IL-1beta, a pleiotropic molecule with a wide spectrum of activities including metabolic, physiologic, hematologic, and immunologic effects. The antibody did not react with chicken IL-18.

The specificity of the original format of this antibody was confirmed by ELISA analysis (Lee et al, 2014; pmid: 25037821). The antibody detected chIL-1beta protein by Western blot analysis. The antibody was used as a capture antibody for measuring serum IL-1B levels in chicken by capture ELISA analysis. The original format of the antibody was used to localize IL-1beta-secreting cells in chicken immune tissues. The antibody neutralized the bioactivity of chIL-1B-induced cell proliferation and NO production by primary thymocytes (Lee et al, 2014; pmid: 25037821).

Western Blot, ELISA, ImmunoHistoChemistry, Neutralisation/Blocking

ELISA; WB; neutralizing; IH

Research Use Only

Monoclonal

1

IL1B

interleukin 1, beta

IL-1 beta; IL1beta; IL-1BETA; interleukin-1 beta

Mouse

IgG2b

Interleukin-1

Chicken

Chicken

The original antibody was raised immunising BALB/C mice with recombinant chicken IL-1B protein.

-20°C,2°C to 8°C

12352203