Anti-IL-1B [IC8]
AB03654-23.0
ApplicationsNeutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetIL1B
Overview
- SupplierAbsolute Antibody
- Product NameAnti-IL-1B [IC8]
- Delivery Days Customer9
- Antibody SpecificityThis antibody binds human Interleukin-1 beta, which is a potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production,
- Application Supplier NoteThis antibody is the humanized version of original mouse antibody IC8. This antibody binds human IL-1B with a binding affinity of Kd= 0.28 nM. The Fab version of this antibody was reported to neutralize IL-1B activity both in an in vitro and an in vivo assay (US7608694).
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDIC8
- Gene ID3553
- Target nameIL1B
- Target descriptioninterleukin 1 beta
- Target synonymscatabolin; IL-1; IL-1 beta; IL1beta; IL1-BETA; IL1F2; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
- HostRabbit
- IsotypeIgG
- Protein IDP01584
- Protein NameInterleukin-1 beta
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203