Anti-IL-33 [309h]

Absolute Antibody

Anti-IL-33 [309h]

9

This antibody binds an epitope between amino acid residues Ser112-Thr270 of the human IL-33. Interleukin 33 (IL-33) is a multifunctional cytokine which is constitutively expressed in structural cells such as smooth muscle cells, fibroblasts, mast cells, d

The humanized IgG1 version of this antibody binds human IL-33 and blocks the binding of human IL-33 to IL-33R-ECD-HFC with an IC50 of 65.93ng/ml. The binding characterization of this antibody to human IL-33 was done using ELISA. This antibody was reported to inhibit IL-33 induced secretion of IL-5 by KU812 cells (CN112480252).

Functional Assay, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

309h

IL33

interleukin 33

C9orf26; DVS27; DVS27-related protein; IL1F11; interleukin-1 family member 11; interleukin-33; NFEHEV; NF-HEV; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules

Rabbit

IgG

Interleukin-33

Human

-20°C,2°C to 8°C

12352203