anti-IL1 beta antibody [DF8] (azide free)
ARG23869
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityPorcine
TargetIL1B
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-IL1 beta antibody [DF8] (azide free)
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDDF8
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID397122
- Target nameIL1B
- Target descriptioninterleukin 1 beta
- Target synonymsIL-1 beta; IL1B1; interleukin 1, beta 1; interleukin-1 beta; prointerleukin-1 beta
- HostMouse
- IsotypeIgG1
- Scientific DescriptionIL1 beta protein is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- ReactivityPorcine
- Storage Instruction-20°C
- UNSPSC12352203