anti-IL22 antibody
ARG54647
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetIL22
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-IL22 antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID50616
- Target nameIL22
- Target descriptioninterleukin 22
- Target synonymscytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-21; IL-22; IL-D110; ILTIF; IL-TIF; interleukin-22; TIFa; TIFIL-23; zcyto18
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInterleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3).
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203