Anti-inflammatory agent 55 [2924156-51-2]

TargetMol Chemicals

Anti-inflammatory agent 55 [2924156-51-2]

72

Chemical

Research Use Only

Anti-inflammatory agent 55

C17H15N3O7

373.32

Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-kappaB pathway and reducing the expression of iNOS, TNF-alpha, IL-6, and IL-1beta. It notably suppresses LPS-induced nitric oxide (NO) production in RAW264.7 macrophages with an IC50 of 0.8 microM and demonstrates anti-inflammatory effects in vivo using a mouse auricular edema model [1].

3 years

O=[N+](C1=CC=C(O1)/C=C/C(NCCN2C3=CC=C(OC)C=C3OC2=O)=O)[O-]

-20°C

12352200