Anti-inflammatory agent 65

MedChem Express

Anti-inflammatory agent 65

14

Research Use Only

C49H71NO6S2

834.22

Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-kappaB signaling pathway, thereby attenuating the inflammatory response [1] .

C[C@@]1(COC(CCCNC(CCCC[C@H]2SSCC2)=O)=O)C(CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)CC[C@@](C(OCC7=CC=CC=C7)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H])=O

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