Anti-Integrin alpha 6 beta 1 [TS2/16]

Absolute Antibody

Anti-Integrin alpha 6 beta 1 [TS2/16]

9

The antibody is specific for human integrin alpha 6 beta 1. It does not cross-react with mouse integrin beta1.

The antibody immunoprecipitated the 130 kDa beta1 form of in U87MG cells. Flow cytometry analysis performed with the antibody confirmed that it could recognise beta1-A172 cells (Bartik et al., 2008; PMID: 18425328). The structure of the Fv-clasp fragment of the antibody was determined. Further, the crystal structure of the a6b1 headpiece complexed with Fv-clasp was determined (Arimori et al., 2017; PMID: 28919443). The antibody increased integrin beta1 in vitro and in vivo (Ritsma et al., 2017; PMID: 28448494)

Flow Cytometry, ImmunoPrecipitation, Other Application

Research Use Only

Monoclonal

TS2/16

ITGA6

integrin subunit alpha 6

CD49 antigen-like family member F; CD49f; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6B; VLA-6

Human

IgG1

Integrin beta-1

Human

-20°C,2°C to 8°C

12352203