Anti-Islet beta cells autoantigen [H116]

Absolute Antibody

Anti-Islet beta cells autoantigen [H116]

9

This antibody is specific for an unknown autoantigen (still under investigation, as of 2016), expressed in islet beta cells (also referred to as intraislet).

This antibody recognizes antigenic determinants selectively expressed in islet beta-cells of the pancreas, as determined by immunofluorescence (IF) staining; its staining pattern mimics the pattern obtained with anti-insulin antibodies. Furthermore, this antibody was shown to be cross-reactive with stomach and kidney cryosections of NOD.RAG-2-/- mice (Carrillo et al., 2005; PMID: 15616012). This antibody was also used for tissue immunostaining of pancreatic cryosections from NOD.RAG-2-/- mice (Carrascal et al., 2016; PMID: 26639224).

ImmunoFluorescence

Research Use Only

Monoclonal

H116

Mouse

IgG1

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203