anti-JAM-C antibody [CRAM-18 F26] (FITC)
ARG23310
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse
TargetJam3
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-JAM-C antibody [CRAM-18 F26] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCRAM-18 F26
- Concentration0.1 mg/ml
- ConjugateFITC
- Gene ID83964
- Target nameJam3
- Target descriptionjunction adhesion molecule 3
- Target synonyms1110002N23Rik; JAM-; JAM-3; JAM-C; Jcam; Jcam3; junction cell adhesion molecule 3; junction cell adhesion molecule C; junctional adhesion molecule 3; junctional adhesion molecule C
- HostRat
- IsotypeIgG2a
- Scientific DescriptionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203