Anti-JMJD6 [APSR-14.4]

Absolute Antibody

Anti-JMJD6 [APSR-14.4]

9

APSR-14.4 was shown crystallographically to bind the C-terminal helix-turn-helix domain of JMJD6 (Hong et al, 2010). JMJD6 was initially identified as a phosphatidylserine receptor, but is now known to be a multifunctional histone modifier which may also

The APSR-14.4 Fab region was used to facilitate crystallisation of JMJD6 (Hong et al, 2010). The mAb has also been used to identify JMJD6 both using Western blot as well as by immunofluorescent staining of of 293 cells (National Jewish Medical and Research Center, unpublished).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, Other Application

Research Use Only

Monoclonal

APSR-14.4

JMJD6

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

arginine demethylase and lysine hydroxylase; bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; histone arginine demethylase JMJD6; jmjC domain-containing protein 6; jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; peptide-lysine 5-dioxygenase JMJD6; phosphatidylserine receptor; PSR; PTDSR; PTDSR1

Human

IgG1

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

This chimeric human antibody was made using the variable domain sequences of the original Hamster IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203