anti-KCNA1 / Kv1.1 antibody

Arigo Biolaboratories

anti-KCNA1 / Kv1.1 antibody

23

ImmunoFluorescence, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

KCNA1

potassium voltage-gated channel subfamily A member 1

AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); RBK1; voltage-gated K(+) channel HuKI; voltage-gated potassium channel HBK1; voltage-gated potassium channel subunit Kv1.1

Rabbit

IgG

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]

Human

-20°C

12352203