Anti-Kv2.1 K+ channel pS603 [L61/14R]

Absolute Antibody

Anti-Kv2.1 K+ channel pS603 [L61/14R]

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This antibody is specific for Kv2.1. Kv2.1 is a voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulati

Immunoblotting was preformed on Kv2.1-KO and AMIGO-KO mouse brain samples (Mandikian et al, 2014; PMID:24962901). immunohistochemistry against brain samples from wild-type mice subjected to CO2 inhalation was preformed with this antibody (Mandikian et al, 2014; PMID:24962901). This antibody was validated with ELISA on rat Kv2.1 amino acids 595-616 (Mandikian et al, 2014; PMID:24962901). COS-1 and CHO cells expressing Kv channels were used for immunofluorescence with this antibody (Cobb et al, 2015; PMID:26442584). COS-1 and CHO cell lysates transfected with transfected with rat Kv2.1, Kv1.4, or Kv2.1 were immunoblotted with this antibody (Cobb et al, 2015; PMID:26442584).

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

WB; IHC; ELISA; IF

Research Use Only

Monoclonal

L61/14R

Rat

IgG2b

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Rat

rat

This antibody was raised by immunizing a mouse with the pS603 phosphopeptide.

-20°C,2°C to 8°C

12352203