Anti-Lactate Dehydrogenase (LDH)

Applied Biological Materials

Anti-Lactate Dehydrogenase (LDH)

9

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Polyclonal

Goat

Goat polyclonal to Lactate Dehydrogenase.Lactate dehydrogenase (LDH) is present in a wide variety of organisms, including plants and animals. It is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called Hydroxybutyrate Dehydrogenase (HBD). There are 5 different isoenzymes of LDH, LDH1 to LDH5, each composed of 4 subunits which may be of 2 different types - M and H subunits. These subunits are encoded by two different genes: The M subunit is encoded by gene LDHA whilst the H subunit is encoded by LDHB. Usually LDH2 is the predominant form in the serum. An LDH1 level higher than the LDH2 level suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH1, into the bloodstream). Suitable for immunoblotting (western or dot blot), ELISA, conjugation and most immunological methods requiring high titer and specificity.

Human

-20°C,2°C to 8°C

12352203