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Anti-LAG-3 [209B1]

Ab03508-23.0
Absolute Antibody
ApplicationsNeutralisation/Blocking, Other Application
Product group Antibodies
ReactivityHuman
TargetLAG3
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-LAG-3 [209B1]
  • Delivery Days Customer
    7
  • Antibody Specificity
    The antibody is specific for human LAG-3.
  • Application Supplier Note
    The antibody is a humanized version of the mouse antibody MAB209B1. The binding affinity of the antibody to hLAG-3 was measured by surface plasmon resonance. The binding affinity of this antibody towards human LAG-3 was found to be Kd= 7.7pM. The antibody showed a good tumour inhibitory effect in in vivo application (WO2021136392).
  • Applications
    Neutralisation/Blocking, Other Application
  • Applications Supplier
    SPR; inhibition
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    209B1
  • Gene ID3902
  • Target name
    LAG3
  • Target description
    lymphocyte activating 3
  • Target synonyms
    CD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP18627
  • Protein Name
    Lymphocyte activation gene 3 protein
  • Scientific Description
    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG4 format for improved compatibility with existing reagents assays and techniques.
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    The original antibody was generated by immunizing female BALB/c mice with Flag-his-tagged extracellular domain of LAG-3.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203