Anti-LAM [BJRbL03]

Absolute Antibody

Anti-LAM [BJRbL03]

7

This antibody is specific for the LAM protein of Mycobacterium tuberculosis but shows cross-reactivity with other Mycobacterium species like M. bovis. M. tuberculosis causes the disease tuberculosis.

The ability of the rabbit version of this antibody to bind LAM was determined using ELISA on LAM. Furthermore, the affinity of this antibody to LAM was determined using a ForteBio Octe machine. Finally, the ability of this antibody to distinguish isolates of M. tuberculosis (MTB), M. avium-intracellulare (MAI), M. abscessus, and M. fortuitum-abscessus (MA-MF) was assessed using flow cytometry; it bound all bacteria (Yan et al., 2021; PMID: 32146163). This antibody was used as a capture antibody in a sandwich ELISA (Yan et al., 2023; PMID: 37764103).

Functional Assay, Flow Cytometry, ELISA

ELISA; FC; functional assay

Research Use Only

Monoclonal

BJRbL03

Rabbit

IgG

Bacteria

Mycobacterium tuberculosis

This antibody was generated by immunizing a rabbit with Mycobacterium tuberculosis H37Rv cell wall.

-20°C,2°C to 8°C

12352203