Anti-Laminin [A5]

Absolute Antibody

Anti-Laminin [A5]

7

This antibody recognizes and precipitates laminin, a macromolecule prevalent in the basement membrane responsible for the attachment of cells to each other and forming tissue in the embryonic development of an organism.

This original rat IgG2a clone can be used to detect and analyze the presence of laminin. The specificity towards this protein has been confirmed using immunoprecipitation (Ljubimov et al., 1986; PMID: 3522258). The location of the laminin was confirmed to be in the basment membrane by means of immunofluorescence using this antibody (Eriksdotter-Nielson et al., 1986; PMID: 3537540).

ImmunoFluorescence, ImmunoPrecipitation, ImmunoHistoChemistry

IP; IHC; IF

Research Use Only

Monoclonal

A5

LAMC1

laminin subunit gamma 1

LAMB2; laminin B2 chain; laminin subunit gamma-1; laminin, gamma 1 (formerly LAMB2); laminin-10 subunit gamma; laminin-11 subunit gamma; laminin-2 subunit gamma; laminin-3 subunit gamma; laminin-4 subunit gamma; laminin-6 subunit gamma; laminin-7 subunit gamma; laminin-8 subunit gamma; laminin-9 subunit gamma; S-LAM gamma; S-laminin subunit gamma

Human

IgG1

Laminin subunit gamma-1

This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Bovine, Human, Mouse

Human, Mouse, Bovine

The original rat IgG2a version of this antibody was raised by immunizing fisher rats with high molecular mass material from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG, and fusing the spleen cells of these rats with mouse myeloma X63 Ag8.653 cells.

-20°C,2°C to 8°C

12352203