Anti-LgR5 [1-12]

Absolute Antibody

Anti-LgR5 [1-12]

9

The antibody is specific for human LgR5. The antibody binds an epitope outside the region of amino acids 22 to 322 of human LgR5.

The specificity of the original format of the antibody was confirmed by ELISA analysis. The original format of the antibody could recognise human LgR5 expressed in 293 cells by FACS. The original format of the antibody was used to detect expression of LgR5 on normal human tissues by immunohistochemistry. The antibody stained normal intestinal crypts in the expected pattern. The antibody also showed moderate staining in hair follicle, and weak staining in fallopian tube, endometrium, adrenal gland, and spinal cord. Further, the antibody detected LgR5 in different colon cancer cell lines (SW403, SW948, CACO-2, T84, KM-12, C2BBel, SW1463, SK-CO-1, LOVO) by immunohistochemistry (US20190248889).

Flow Cytometry, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

1-12

LGR5

leucine rich repeat containing G protein-coupled receptor 5

FEX; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine-rich repeat-containing G-protein coupled receptor 5; orphan G protein-coupled receptor HG38

Rabbit

IgG

Leucine-rich repeat-containing G-protein coupled receptor 5

Human

-20°C,2°C to 8°C

12352203