Anti-Lipoteichoic acid [A120]

Absolute Antibody

Anti-Lipoteichoic acid [A120]

9

This antibody targets the lipoteichoic acid (LTA) which is a major cell wall component of gram positive bacteria. LTA plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock.

This antibody shows high opsonic acitivty against S. aureus type 5 and S. epidermidis strain Hay, killing 95% of S. epidermidis and an average of 82% of S. aureus at 200 [mu]g/ml. The binding activity of A120 to LTA was confirmed with ELISA.

ELISA

Research Use Only

Monoclonal

A120

Human

IgG1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Bacteria

-20°C,2°C to 8°C

12352203