Anti-LMP1 [H11F6]

Absolute Antibody

Anti-LMP1 [H11F6]

7

This antibody specifically binds the CTAR1/TES1 (C terminus activation region 1/transformation effector site 1) which comprises the membrane-most proximal 34 amino acids (amino acid residues 196-231) of carboxy-terminal cytoplasmic tail of the oncogenic l

The binding characterization of this antibody to the TES1 polypeptide of the LMP1 protein of Epstein-Barr virus was done using ELISA. This antibody can selectively block F-LMP1-induced NFkappaB activity that was mediated through the TES1-site and to bind LMP1 protein with high efficiency (PMID: 14659750).

ELISA

ELISA

Research Use Only

Monoclonal

H11F6

LMP-1

latent membrane protein LMP-1

HHV4_LMP-1; latent membrane protein LMP-1

Rabbit

IgG

Latent membrane protein 1

This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Virus

Epstein Barr virus, Human herpesvirus 4

The original antibody was isolated from a human non-immune scFv phage display library by screening antibodies against a 44-mer polypeptide corresponding to the CTAR1/TES1 site of LMP1 (TES1 polypeptide).

-20°C,2°C to 8°C

12352203