anti-LONP1 / Lon antibody

Arigo Biolaboratories

anti-LONP1 / Lon antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1.6 mg/ml

Unconjugated

LONP1

lon peptidase 1, mitochondrial

CODASS; hLON; hLON ATP-dependent protease; LON; lon protease homolog, mitochondrial; LonHS; LONP; mitochondrial ATP-dependent protease Lon; mitochondrial lon protease-like protein; PIM1; PRSS15; serine protease 15

Rabbit

IgG

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]

Human

-20°C

12352203