Anti-LRP Light Chain [8B8]

Absolute Antibody

Anti-LRP Light Chain [8B8]

7

This antibody is specific for LRP1, and reacts with an epitope in the 85kDa light beta chain (LRP-85 subunit).

The specificity of this antibody has been confirmed in immunoblotting experiments (Strickland et al, 1990). This antibody has been used in Western blot analysis of HEK-293 cells transfected with human full-length LRP1 fused to EGFP, to confirm fusion protein expression (Laatsch et al, 2012). Additionally, this antibody has been used in Western blot analysis to measure LRP1 protein expression levels, both in human vascular smooth muscle cells (Costales et al, 2015; Sendra et al, 2008) and human monocyte-derived macrophages (Llorente-Cortes et al, 2007).

Western Blot

IB; WB

Research Use Only

Monoclonal

8B8

LRP1

LDL receptor related protein 1

A2MR; alpha-2-macroglobulin receptor; APOER; apolipoprotein E receptor; APR; CD91; IGFBP3R; IGFBP-3R; IGFBP3R1; KPA; low density lipoprotein receptor-related protein 1; LRP; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor

Rat

IgG2b

Prolow-density lipoprotein receptor-related protein 1

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rabbit, Rat

Human, Mouse, Rat, Rabbit

This antibody was raised by immunising mice with human LRP, purified by affinity chromatography from detergent placenta extracts.

-20°C,2°C to 8°C

12352203