anti-Ly 6C antibody [ER-MP20] (Biotin)
ARG22861
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetLy6c1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Ly 6C antibody [ER-MP20] (Biotin)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDER-MP20
- Concentration0.1 mg/ml
- ConjugateBiotin
- Gene ID17067
- Target nameLy6c1
- Target descriptionlymphocyte antigen 6 complex, locus C1
- Target synonymsAA682074; AA959465; Ly6; Ly-6; Ly6c; Ly-6C; Ly-6C1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C1; Lymphocyte antigen Ly-6C
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThis gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203