anti-Ly 6C antibody [ER-MP20] (PE)

Arigo Biolaboratories

anti-Ly 6C antibody [ER-MP20] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

ER-MP20

RPE

Ly6c1

lymphocyte antigen 6 complex, locus C1

AA682074; AA959465; Ly6; Ly-6; Ly6c; Ly-6C; Ly-6C1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C1; Lymphocyte antigen Ly-6C

Rat

IgG2a

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Mouse

2°C to 8°C

12352203