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anti-Ly 6C antibody [ER-MP20] (PE)

ARG22863
Arigo Biolaboratories
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetLy6c1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Ly 6C antibody [ER-MP20] (PE)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ER-MP20
  • Conjugate
    RPE
  • Gene ID17067
  • Target name
    Ly6c1
  • Target description
    lymphocyte antigen 6 complex, locus C1
  • Target synonyms
    AA682074; AA959465; Ly6; Ly-6; Ly6c; Ly-6C; Ly-6C1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C1; Lymphocyte antigen Ly-6C
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203