Anti-M-CSF [252], Human IgG1, Fc Silent(tm), kappa

Absolute Antibody

Anti-M-CSF [252], Human IgG1, Fc Silent(tm), kappa

9

The antibody is specific for M-CSF.

The original format of the antibody inhibited mouse monocytic cell proliferation in response to M-CSF. Further, the IC50 for inhibition of mouse nonocytic cell proliferation was determined for the antibody (IC50 = 86.7 nM). The binding properties of the original format of the antibody were analyzed using SPR analysis (Kd= 0.13 pM) (US7326414B2).

Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

252

CSF1

colony stimulating factor 1

colony stimulating factor 1 (macrophage); CSF-1; lanimostim; macrophage colony stimulating factor 1; macrophage colony-stimulating factor 1; MCSF

Human

IgG1

Macrophage colony-stimulating factor 1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203